treat rat p1 p2 p3 p4 P 1 7.5 8.6 6.9 0.8 P 2 10.6 11.7 8.8 1.6 P 3 12.4 13.0 11.0 5.6 P 4 11.5 12.6 11.1 7.5 P 5 8.3 8.9 6.8 0.5 P 6 9.2 10.1 8.6 3.8 N 7 13.3 13.3 12.9 11.1 N 8 10.7 10.8 10.7 9.3 N 9 12.5 12.7 12.0 10.1 N 10 8.4 8.7 8.1 5.7 N 11 9.4 9.6 8.0 3.8 N 12 11.3 11.7 10.0 8.5