group subject week cholest drug 1 4 317 drug 1 8 280 drug 1 12 275 drug 1 16 270 drug 1 20 274 drug 1 24 266 drug 2 4 186 drug 2 8 189 drug 2 12 190 drug 2 16 135 drug 2 20 197 drug 2 24 205 drug 3 4 377 drug 3 8 395 drug 3 12 368 drug 3 16 334 drug 3 20 338 drug 3 24 334 drug 4 4 229 drug 4 8 258 drug 4 12 282 drug 4 16 272 drug 4 20 264 drug 4 24 265 drug 5 4 276 drug 5 8 310 drug 5 12 306 drug 5 16 309 drug 5 20 300 drug 5 24 264 drug 6 4 272 drug 6 8 250 drug 6 12 250 drug 6 16 255 drug 6 20 228 drug 6 24 250 drug 7 4 219 drug 7 8 210 drug 7 12 236 drug 7 16 239 drug 7 20 242 drug 7 24 221 drug 8 4 260 drug 8 8 245 drug 8 12 264 drug 8 16 268 drug 8 20 317 drug 8 24 314 drug 9 4 284 drug 9 8 256 drug 9 12 241 drug 9 16 242 drug 9 20 243 drug 9 24 241 drug 10 4 365 drug 10 8 304 drug 10 12 294 drug 10 16 287 drug 10 20 311 drug 10 24 302 drug 11 4 298 drug 11 8 321 drug 11 12 341 drug 11 16 342 drug 11 20 357 drug 11 24 335 drug 12 4 274 drug 12 8 245 drug 12 12 262 drug 12 16 263 drug 12 20 235 drug 12 24 246 placebo 13 4 232 placebo 13 8 205 placebo 13 12 244 placebo 13 16 197 placebo 13 20 218 placebo 13 24 233 placebo 14 4 367 placebo 14 8 354 placebo 14 12 358 placebo 14 16 333 placebo 14 20 338 placebo 14 24 355 placebo 15 4 253 placebo 15 8 256 placebo 15 12 247 placebo 15 16 228 placebo 15 20 237 placebo 15 24 235 placebo 16 4 230 placebo 16 8 218 placebo 16 12 245 placebo 16 16 215 placebo 16 20 230 placebo 16 24 207 placebo 17 4 190 placebo 17 8 188 placebo 17 12 212 placebo 17 16 201 placebo 17 20 169 placebo 17 24 179 placebo 18 4 290 placebo 18 8 263 placebo 18 12 291 placebo 18 16 312 placebo 18 20 299 placebo 18 24 279 placebo 19 4 337 placebo 19 8 337 placebo 19 12 383 placebo 19 16 318 placebo 19 20 361 placebo 19 24 341 placebo 20 4 283 placebo 20 8 279 placebo 20 12 277 placebo 20 16 264 placebo 20 20 269 placebo 20 24 271 placebo 21 4 325 placebo 21 8 257 placebo 21 12 288 placebo 21 16 326 placebo 21 20 293 placebo 21 24 275 placebo 22 4 266 placebo 22 8 258 placebo 22 12 253 placebo 22 16 284 placebo 22 20 245 placebo 22 24 263 placebo 23 4 338 placebo 23 8 343 placebo 23 12 307 placebo 23 16 274 placebo 23 20 262 placebo 23 24 309