subject placebo old new old-placebo new-old 1 9243 17649 16449 8406 -1200 2 9671 12013 14614 2342 2601 3 11792 19979 17274 8187 -2705 4 13357 21816 23798 8459 1982 5 9055 13850 12560 4795 -1290 6 6290 9806 10157 3516 351 7 12412 17208 16570 4796 -638 8 18806 29044 26325 10238 -2719