treat rat period y P 1 p1 7.5 P 1 p2 8.6 P 1 p3 6.9 P 1 p4 0.8 P 2 p1 10.6 P 2 p2 11.7 P 2 p3 8.8 P 2 p4 1.6 P 3 p1 12.4 P 3 p2 13.0 P 3 p3 11.0 P 3 p4 5.6 P 4 p1 11.5 P 4 p2 12.6 P 4 p3 11.1 P 4 p4 7.5 P 5 p1 8.3 P 5 p2 8.9 P 5 p3 6.8 P 5 p4 0.5 P 6 p1 9.2 P 6 p2 10.1 P 6 p3 8.6 P 6 p4 3.8 N 7 p1 13.3 N 7 p2 13.3 N 7 p3 12.9 N 7 p4 11.1 N 8 p1 10.7 N 8 p2 10.8 N 8 p3 10.7 N 8 p4 9.3 N 9 p1 12.5 N 9 p2 12.7 N 9 p3 12.0 N 9 p4 10.1 N 10 p1 8.4 N 10 p2 8.7 N 10 p3 8.1 N 10 p4 5.7 N 11 p1 9.4 N 11 p2 9.6 N 11 p3 8.0 N 11 p4 3.8 N 12 p1 11.3 N 12 p2 11.7 N 12 p3 10.0 N 12 p4 8.5