EDI: Experimental Design and Inference

Implements a comprehensive suite of experimental designs, both fixed (e.g., block, stratified, matched-pair, cluster, factorial, and mixed-integer-programming-based optimal designs) and sequential (including matching-on-the-fly designs, biased coin designs, and covariate-adaptive urn designs that assign treatment one subject at a time while maintaining covariate balance), for continuous, incidence, count, proportion, survival, and ordinal response types. For each design and response type combination, provides the corresponding inference procedures, including exact, asymptotic, distribution-free, and resampling-based (bootstrap, jackknife, and randomization) methods, so that estimation and testing are always matched to how the data were generated. An 'InferenceSuite' facility runs all applicable inference procedures for a given design and response type at once and reports a single Cauchy-combined p-value summarizing their evidence. A built-in simulation framework supports power analysis and operating-characteristic studies across designs, response types, and inference procedures, with optional parallelization via 'mirai'. Missing covariate data is handled automatically via built-in imputation. Core numerical routines are implemented in C++ via 'Rcpp' for speed on large designs and simulation studies. Machine-specific tuning for optimization is included.

Version:	1.0.2
Depends:	R (≥ 3.5.0)
Imports:	R6, checkmate, Rcpp, data.table, survival, missRanger, missForest, numDeriv, digest, methods, MASS, RhpcBLASctl, randomizr
LinkingTo:	Rcpp, RcppEigen, RcppNumerical
Suggests:	anticlust, blockTools, clinfun, coin, dplyr, mirai, aftgee, betareg, copula, doParallel, ggplot2, fixest, gamlss.dist, geepack, glmmTMB, glmnet, icenReg, interval, jsonlite, knitr, lme4, multgee, nbpMatching, nlme, nnet, ordinal, pscl, qpdf, quantreg, R.utils, RcppXPtrUtils, Rfit, rmarkdown, testthat, VGAM, ompr, ompr.roi, ROI.plugin.glpk, sandwich, withr
Published:	2026-10-07
DOI:	10.32614/CRAN.package.EDI (may not be active yet)
Author:	Adam Kapelner [aut, cre, cph]
Maintainer:	Adam Kapelner <adam.kapelner at mail.huji.ac.il>
BugReports:	https://github.com/kapelner/EDI/issues
License:	GPL-3
Copyright:	see file COPYRIGHTS
URL:	https://github.com/kapelner/EDI, https://kapelner.github.io/EDI/, https://pypi.org/project/edi-kernels/
NeedsCompilation:	yes
Language:	en-US
Citation:	EDI citation info
Materials:	README, NEWS
CRAN checks:	EDI results

Documentation:

Reference manual:

EDI.html , EDI.pdf

Vignettes:

Backend Contracts: fast_* and C++ Utilities (source, R code) Cookbook: Continuous Outcome, End to End (source, R code) Cookbook: Count Outcome, End to End (source, R code) Cookbook: Incidence (Binary) Outcome, End to End (source, R code) Cookbook: Ordinal Outcome, End to End (source, R code) Cookbook: Proportion Outcome, End to End (source, R code) Cookbook: Survival Outcome with Censoring, End to End (source, R code) Extending EDI with Your Own Inference and Design Classes (source, R code) Notation Glossary (source, R code) Reproducibility: RNG and Seed Conventions (source, R code) Validation Evidence (source, R code)

Downloads:

Package source:	EDI_1.0.2.tar.gz
Windows binaries:	r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries:	r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available

Linking:

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