IDMIR: Identification of Dysregulated MiRNAs Based on MiRNA-MiRNA Interaction Network

A systematic biology tool was developed to identify dysregulated miRNAs via a miRNA-miRNA interaction network. 'IDMIR' first constructed a weighted miRNA interaction network through integrating miRNA-target interaction information, molecular function data from Gene Ontology (GO) database and gene transcriptomic data in specific-disease context, and then, it used a network propagation algorithm on the network to identify significantly dysregulated miRNAs.

Version: 0.1.0
Depends: R (≥ 2.10)
Imports: egg, fastmatch, forestplot, ggplot2, grDevices, grid, igraph, pheatmap, survival, survminer
Suggests: knitr, rmarkdown
Published: 2023-11-09
DOI: 10.32614/CRAN.package.IDMIR
Author: Junwei Han [aut, cre, cph], Xilong Zhao [aut], Jiashuo Wu [aut]
Maintainer: Junwei Han <hanjunwei1981 at 163.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: IDMIR results

Documentation:

Reference manual: IDMIR.pdf
Vignettes: IDMIR User Guide

Downloads:

Package source: IDMIR_0.1.0.tar.gz
Windows binaries: r-devel: IDMIR_0.1.0.zip, r-release: IDMIR_0.1.0.zip, r-oldrel: IDMIR_0.1.0.zip
macOS binaries: r-release (arm64): IDMIR_0.1.0.tgz, r-oldrel (arm64): IDMIR_0.1.0.tgz, r-release (x86_64): IDMIR_0.1.0.tgz, r-oldrel (x86_64): IDMIR_0.1.0.tgz

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