SubgrpID: Patient Subgroup Identification for Clinical Drug Development

Implementation of Sequential BATTing (bootstrapping and aggregating of thresholds from trees) for developing threshold-based multivariate (prognostic/predictive) biomarker signatures. Variable selection is automatically built-in. Final signatures are returned with interaction plots for predictive signatures. Cross-validation performance evaluation and testing dataset results are also output. Detail algorithms are described in Huang et al (2017) <doi:10.1002/sim.7236>.

Version: 0.12
Imports: glmnet, MASS, rpart, survival, Matrix, ggplot2
Published: 2024-02-03
DOI: 10.32614/CRAN.package.SubgrpID
Author: Xin Huang [aut, cre, cph], Yan Sun [aut], Saptarshi Chatterjee [aut], Paul Trow [aut]
Maintainer: Xin Huang <xin.huang at abbvie.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: SubgrpID results

Documentation:

Reference manual: SubgrpID.pdf

Downloads:

Package source: SubgrpID_0.12.tar.gz
Windows binaries: r-devel: SubgrpID_0.12.zip, r-release: SubgrpID_0.12.zip, r-oldrel: SubgrpID_0.12.zip
macOS binaries: r-release (arm64): SubgrpID_0.12.tgz, r-oldrel (arm64): SubgrpID_0.12.tgz, r-release (x86_64): SubgrpID_0.12.tgz, r-oldrel (x86_64): SubgrpID_0.12.tgz
Old sources: SubgrpID archive

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