TRD: Transmission Ratio Distortion

Transmission Ratio Distortion (TRD) is a genetic phenomenon where the two alleles from either parent are not transmitted to the offspring at the expected 1:1 ratio under Mendelian inheritance, leading to spurious signals in genetic association studies. Functions in this package are developed to account for this phenomenon using loglinear model and Transmission Disequilibrium Test (TDT). Some population information can also be calculated.

Version: 1.1
Depends: Rlab (≥ 2.15.1)
Published: 2015-11-11
DOI: 10.32614/CRAN.package.TRD
Author: Lam Opal Huang
Maintainer: Lam Opal Huang <opal.huang at mail.mcgill.ca>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: TRD results

Documentation:

Reference manual: TRD.pdf

Downloads:

Package source: TRD_1.1.tar.gz
Windows binaries: r-devel: TRD_1.1.zip, r-release: TRD_1.1.zip, r-oldrel: TRD_1.1.zip
macOS binaries: r-release (arm64): TRD_1.1.tgz, r-oldrel (arm64): TRD_1.1.tgz, r-release (x86_64): TRD_1.1.tgz, r-oldrel (x86_64): TRD_1.1.tgz
Old sources: TRD archive

Linking:

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