Methods to evaluate the performance characteristics of
various point and interval estimators for optimal adaptive two-stage designs as described
in Meis et al. (2024) <doi:10.1002/sim.10020>.
Specifically, this package is written to work with trial designs created by the 'adoptr' package
(Kunzmann et al. (2021) <doi:10.18637/jss.v098.i09>; Pilz et al. (2021) <doi:10.1002/sim.8953>)).
Apart from the a priori evaluation of performance characteristics, this package also allows for the
evaluation of the implemented estimators on real datasets, and it implements methods
to calculate p-values.
| Version: |
1.0.0 |
| Depends: |
R (≥ 4.0.0), adoptr |
| Imports: |
methods, stats, grDevices, cubature, ggplot2, ggpubr, scales, latex2exp, forcats, future.apply, progressr, Rdpack |
| Suggests: |
covr, knitr, rmarkdown, testthat (≥ 3.0.0), microbenchmark |
| Published: |
2024-07-12 |
| DOI: |
10.32614/CRAN.package.adestr |
| Author: |
Jan Meis  [aut,
cre],
Martin Maechler
[cph] (Original author of monoSpl.c (from the 'stats' package).) |
| Maintainer: |
Jan Meis <meis at imbi.uni-heidelberg.de> |
| License: |
GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| Copyright: |
This package contains a modified version of the monotonic
spline functions from the 'stats' package. Specifically, the
code is containted in the files 'R/fastmonoHFC.R',
'src/fastmonoHFC.c', 'src/modreg.h' and 'src/monoSpl.c'. The R
Core team and Martin Maechler are the copyright holders of the
original code. Jan Meis is the copyright holder of everything
else. |
| URL: |
https://jan-imbi.github.io/adestr/ |
| NeedsCompilation: |
yes |
| Citation: |
adestr citation info |
| Materials: |
README, NEWS |
| In views: |
ClinicalTrials |
| CRAN checks: |
adestr results |