beadplexr: Analysis of Multiplex Cytometric Bead Assays

Reproducible and automated analysis of multiplex bead assays such as CBA (Morgan et al. 2004; <doi:10.1016/j.clim.2003.11.017>), LEGENDplex (Yu et al. 2015; <doi:10.1084/jem.20142318>), and MACSPlex (Miltenyi Biotec 2014; Application note: Data acquisition and analysis without the MACSQuant analyzer; <https://www.miltenyibiotec.com/upload/assets/IM0021608.PDF>). The package provides functions for streamlined reading of fcs files, and identification of bead clusters and analyte expression. The package eases the calculation of standard curves and the subsequent calculation of the analyte concentration.

Version: 0.5.0
Depends: R (≥ 4.3)
Imports: cluster, dplyr, drc, fpc, ggplot2, mclust, purrr, tibble, tidyr, yaml, rlang
Suggests: spelling, gridExtra, hexbin, knitr, rmarkdown, stringr, testthat
Published: 2023-06-16
DOI: 10.32614/CRAN.package.beadplexr
Author: Ulrik Stervbo ORCID iD [aut, cre]
Maintainer: Ulrik Stervbo <ulrik.stervbo at gmail.com>
BugReports: https://gitlab.com/ustervbo/beadplexr/-/issues
License: MIT + file LICENSE
URL: https://gitlab.com/ustervbo/beadplexr
NeedsCompilation: no
Language: en-US
Citation: beadplexr citation info
Materials: README NEWS
CRAN checks: beadplexr results

Documentation:

Reference manual: beadplexr.pdf
Vignettes: beadplexr with CBA and MACSPlex assays
Analysis of LEGENDplex data with 'beadplexr'
Preparing flow-data for use with with 'beadplexr'

Downloads:

Package source: beadplexr_0.5.0.tar.gz
Windows binaries: r-devel: beadplexr_0.5.0.zip, r-release: beadplexr_0.5.0.zip, r-oldrel: beadplexr_0.5.0.zip
macOS binaries: r-release (arm64): beadplexr_0.5.0.tgz, r-oldrel (arm64): beadplexr_0.5.0.tgz, r-release (x86_64): beadplexr_0.5.0.tgz, r-oldrel (x86_64): beadplexr_0.5.0.tgz
Old sources: beadplexr archive

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