## ----setup, include=FALSE----------------------------------------------------- library(knitr) library(ncappc) library(tibble) library(dplyr) opts_chunk$set(echo = FALSE, comment=NA, tidy = TRUE, fig.align = 'center', fig.show='asis', out.width='90%', fig.pos='H') ## ----echo=TRUE,eval=FALSE----------------------------------------------------- # ncappc(obsFile = "file_with_observations.txt") ## ----out.height='90%',out.width='90%',fig.align='center',fig.cap="**Figure 1:** Schematic work-flow of the ```ncappc()``` function in the ***ncappc*** package.",echo = FALSE---- knitr::include_graphics('./ncappc-Schema.png') ## ----echo=TRUE,tidy=FALSE----------------------------------------------------- data_1 <- tibble( ID=1, TIME = c(0,0.25,0.5,1,1.5,2,3,4,6,8,12,16,24), DV=c(0, 0.07, 0.14, 0.21, 0.24, 0.27, 0.26, 0.25, 0.22, 0.19, 0.13, 0.081, 0.033) ) out <- ncappc(obsFile=data_1, onlyNCA = T, extrapolate = T, printOut = F, evid = FALSE, noPlot = T) out$ncaOutput %>% select(c(AUClast,AUCINF_pred,Cmax,Tmax)) ## ----echo=TRUE,eval=FALSE----------------------------------------------------- # ncappc(concUnit="ng/ml", doseAmtNm = "DOSE")