Design and analysis of confirmatory adaptive clinical trials using the optimal conditional error framework according to Brannath and Bauer (2004) <doi:10.1111/j.0006-341X.2004.00221.x>. An extension to the optimal conditional error function using interim estimates as described in Brannath and Dreher (2024) <doi:10.48550/arXiv.2402.00814> and functions to ensure that the resulting conditional error function is non-increasing are also available.
Version: | 1.0.0 |
Imports: | ggplot2, methods |
Suggests: | knitr, rmarkdown, testthat (≥ 3.0.0) |
Published: | 2025-09-09 |
DOI: | 10.32614/CRAN.package.optconerrf |
Author: | Morten Dreher [aut, cre],
Werner Brannath |
Maintainer: | Morten Dreher <morten.dreher at outlook.de> |
BugReports: | https://github.com/morten-dreher/optconerrf/issues |
License: | GPL (≥ 3) |
URL: | https://github.com/morten-dreher/optconerrf |
NeedsCompilation: | no |
Materials: | README, NEWS |
CRAN checks: | optconerrf results |
Reference manual: | optconerrf.html , optconerrf.pdf |
Vignettes: |
Using Constraints and Interim Estimates for the Optimal Conditional Error Function (source, R code) introduction (source, R code) |
Package source: | optconerrf_1.0.0.tar.gz |
Windows binaries: | r-devel: not available, r-release: not available, r-oldrel: not available |
macOS binaries: | r-release (arm64): optconerrf_1.0.0.tgz, r-oldrel (arm64): optconerrf_1.0.0.tgz, r-release (x86_64): optconerrf_1.0.0.tgz, r-oldrel (x86_64): optconerrf_1.0.0.tgz |
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