[BioC] one-color oligo methods

Wolfgang Huber Wolfgang Huber <w.huber@dkfz-heidelberg.de>
Fri, 31 Jan 2003 17:16:55 +0100 (MET)


Hi Dick,

the 'vsn' package does normalization and variance stabilizing
transformation on arbitrary matrices (i.e. rows=probes and
columns=arrays). See the paper and the vignette for details.

It works well for one-color spotted array data (and also for radioactive
membranes.)

Best regards
Wolfgang 

Wolfgang Huber
DKFZ Heidelberg, Germany

On Thu, 30 Jan 2003, Dick Beyer wrote:
> Does anyone have any R scripts they would like to share that would do diagnositics and normalizations for one-color oligo slides, such as Mergen and Amersham Codelink?
> 
> I would like to do multi-array normalization.  
> 
> Thanks much,
> Dick