[BioC] Position in Biostatistics and Bioinformatics

[Sophie Gallina]

Position in Biostatistics and Bioinformatics
Field: Microarray data and complex genetic disease analysis

INSTITUT DE BIOLOGIE DE LILLE
CNRS UMR 8090 - Genetics of Multifactorial Diseases
Lille - FRANCE

A full time POSITION in Biostatistics and Bioinformatics is available 
for 2 years starting November, 2003 in the Department of Human Genetics 
- Genetics of Multifactorial Diseases – CNRS UMR 8090 - Director of 
Unit: Professor Philippe Froguel

Project Description:
Analysis of Affymetrix microarray data from transcriptome experiments 
using animal models and genetic data from human polymorphisms typed in 
both cohort and family studies. This will be carried out in the context 
of exploration of the molecular mechanisms underlying pancreatic 
beta-cell dysfunction and associated insulin-resistance.

Activities:

    * Select and set up appropriate statistical methods for analyzing:
          o Microarray data, including normalization, selection of
            significant expression variation, clustering, GO annotation
          o Genetic data, including linkage analysis, association
            analysis, linkage disequilibrium mapping and haplotype
            construction
    * Manage data (acquisition, validation, quality control, organization)
    * Analyze data, interpret and present results
    * Adapt or develop new statistical tools when necessary
    * Optimize usage of such tools and set up standard analysis procedures
    * Data acquisition from public databases and other online resources


Skills:

    * Knowledge of statistical methods
    * Experience of statistical software such as SPSS, S+ or R
    * Strong experience in microarray data analysis
    * Knowledge of public databases and other online biological resources


Experience:
Masters Degree (DESS) or PhD, and, ideally, practical experience of 
microarray experiments.


Conditions:
The Position is for 2 years, from the 1st of November 2003, in Lille, 
France, in the bioinformatics and biostatistics team (6 people) of the 
Genetics of Multifactorial Diseases Laboratory.
Training in population genetics can be provided by the lab

Application Deadline:
Applications will be reviewed in October 2003 until a suitable candidate 
is identified.
Interviews may begin in late October
Interested applicants should submit a letter of intent, a summary of 
previous research experience and a curriculum vitae, and reference to 
Sophie Gallina:
Sophie.Gallina at mail-good.pasteur-lille.fr 
<mailto:Sophie.Gallina at mail-good.pasteur-lille.fr>