[BioC] Limma FDR question
Sean Davis
sdavis2 at mail.nih.gov
Fri Dec 10 13:50:26 CET 2004
See ?p.adjust for specifics. However, in a particular case, if one has
100 genes with fdr less than 0.05, then 5 out of that 100 are expected
to be false positive. In other words, for any given fdr cutoff x, if
there are N genes with fdr<x, then x*N genes are expected to be false
discoveries.
Sean
On Dec 10, 2004, at 7:21 AM, M PEREZ wrote:
>
> Hi all,
>
> I was wondering how the p-value correction using fdr works.
>
> The following Limma package's command " topTable(fit,number=100,
> adjust="fdr")" corrects the p-values but I don't know which is the
> percent of false positive we can expect using this correction. Is the
> FDR fixing at one pre-determined value, e.g. 5 %?
>
> Thank you in advance
>
> Best,
>
> Manuel
>
>
>
> ---------------------------------
>
>
> [[alternative HTML version deleted]]
>
> _______________________________________________
> Bioconductor mailing list
> Bioconductor at stat.math.ethz.ch
> https://stat.ethz.ch/mailman/listinfo/bioconductor
More information about the Bioconductor
mailing list