[BioC] Re: Suggestion for affycomp
hgoehlma at gmx.de
Mon Jul 19 10:22:02 CEST 2004
hmmm... was my question/suggestion that weird or not understandable
(English is not my native language...) or is there simply no need for
such an overview table?
Hinrich Göhlmann wrote:
> Good morning,
> I have a suggestion for affycomp and it's accompanying web site at
> I very much like the idea to check how the different algorithms perform
> but I would even more appreciate a biologist-compatible interpretation
> of the comparison table (low or no stats!). What I have in mind is
> something like:
> (1) define all the different approaches that people could be interested
> in from a statistical point of view (Example: I am interested in a best
> possible accuracy of fold change estimation at all signal levels. For
> this application, score components 4, 7, and 13 are most important (I
> don't know!). OR: I would like to have the highest possible precision
> for the signal levels. For this application score components 3, 6, 8,
> and 11 are most important. OR: I need best possible precision for low
> expressed genes. For this components x, y, and z are most important. And
> so on...
> (2) make a table with those applications and give the 2 or three best
> suitable algorithms for those applications.
> By openly defining those applications at such a web site, we can get a
> discussion going on what components most people agree on per application
> and can secondly make practical use of the data that gets collected.
> hinrich d8-)
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