[BioC] anova and multiple comparisons
naomi at stat.psu.edu
Fri Jun 25 17:34:38 CEST 2004
I would use limma followed by qvalue (another Bioconductor package). There
are several examples on this mainling list of how to set this up. Check my
message of yesterday for a comment about the correspondance between SAM and
limma for 1-way ANOVA.
At 10:28 AM 6/25/2004 -0500, Kimpel, Mark W wrote:
>I have been using SAM to estimate FDR when performing multiple
>comparisons on two groups. I have now been tasked with performing a
>similar analysis on a 2X2 experiment (2 groups each with two
>treatments). For a single comparison, ANOVA would be the obvious choice.
>What should be my approach for multiple (about a thousand) comparisons?
>Mark W. Kimpel MD
>(317) 490-5129 Home, Work, & Mobile
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Naomi S. Altman 814-865-3791 (voice)
Bioinformatics Consulting Center
Dept. of Statistics 814-863-7114 (fax)
Penn State University 814-865-1348 (Statistics)
University Park, PA 16802-2111
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