[BioC] RMA

[James MacDonald]

Ben Bolstad has done some work on this issue.

http://stat-www.berkeley.edu/users/bolstad/mixtureCDF/MixtureCDF.html

HTH,

Jim



James W. MacDonald
Affymetrix and cDNA Microarray Core
University of Michigan Cancer Center
1500 E. Medical Center Drive
7410 CCGC
Ann Arbor MI 48109
734-647-5623

>>> Willy Wynant <Willy.Wynant at curie.fr> 06/30/04 05:39AM >>>
Hello,

I would like to normalize data from fifty chips with the RMA method.
The problem is that I have both U95A and U95AV2 chips which
seem to differ from around only fifteen probesets. Has anyone already
encountered this problem? Should I have to remove the probesets (on
the
CEL files) which are not the same in the chips, and normalize only the
others?

Thanks a lot for your help,

Regards,

Willy

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