[BioC] Limma and missing data

Sean Davis sdavis2 at mail.nih.gov
Mon Mar 1 21:05:36 MET 2004


I have a very noisy data set that I am having trouble thresholding to get
useful genes, so I am resorting to using missing values.  (Yes, I could
impute, but my n is not huge and consists of four non-distinct groups).  My
question is:

How does limma handle missing data?  It doesn't mind NA's coming in, but
does it correct for the different df at each gene given the number of NA's?

Thanks,
Sean



More information about the Bioconductor mailing list