[BioC] Minimum no. of chips for express/rma/gcrma etc

[Aedin]

Dear BioC
Are rma/gcrma/mas5.0/ etc limited by a minimum number of chip (.cel) files?

I am calling expression values on a dataset with only 2 chips
(treated/control, pooled RNA from n=5). Is 2 chips too few .cel files for
these methods?

Thanks for your help
Aedin