[BioC] Unequally spaced replicates in limma

[michael watson (IAH-C)]

Hi

As I have varying numbers of replicates, and they are not regularly
spaced on the array, and given that I would like a list of
differentially expressed genes which is averaged over replicates, I
assume the best thing to do is normalise my data, and then average over
replicates in the MAList object, and then pass the averaged data to
lmFit() etc?

Is that right?

Cheers
Mick