[BioC] justRMA => logarithmic data ?

Arne.Muller at sanofi-aventis.com Arne.Muller at sanofi-aventis.com
Fri Feb 18 10:31:37 CET 2005


yes, the final output from RMA are log2 transformed.

	Arne

> -----Original Message-----
> From: bioconductor-bounces at stat.math.ethz.ch
> [mailto:bioconductor-bounces at stat.math.ethz.ch]On Behalf Of Heike
> Pospisil
> Sent: 18 February 2005 09:29
> To: bioconductor at stat.math.ethz.ch
> Subject: [BioC] justRMA => logarithmic data ?
> 
> 
> Dear list members,
> 
> I have an additional question concerning my affymetrix analysis.
> 
> I performed justRMA on 79 CEL-files.
> 
> data<-justRMA()
> 
> The resulting expression data range from ~3 to ~14.
> 
> min(exprs(data))
> max(exprs(data))
> 
> Now, only for clarifying, are these values already 
> logarithmised? I have read 
> about the thresholds for the golub data that are much larger 
> (100 and 16,000), 
> but log2(16000)is ~14 - and so I think, that I have already 
> logarithmic data. Am 
> I right?
> 
> Thanks a lot for your help.
> 
> Best wishes,
> Heike
> -- 
> Dr. Heike Pospisil
> Center for Bioinformatics, University of Hamburg
> Bundesstrasse 43, 20146 Hamburg, Germany
> phone: +49-40-42838-7303 fax: +49-40-42838-7312
> 
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