[BioC] Scaling GCRMA intesities

Radu Dobrin dobrin at pa.msu.edu
Thu Jan 27 23:39:25 CET 2005


Hi,

I have been using GCRMA and checking today the histograms it seems that
the distribution (for expressions vals of probes on a single chip) is
not symmetric at all, rather toward left. Is it normal? MAS5 is very
symmetric in distrib of probe intensities (after log2). Also since the
distrib for GCRMA is not symmetric it is wise to scale the data between
chips?

If you have any suggestions please let me know.

Radu

-- 
Dr. Radu Dobrin
Department of Molecular Biology
Princeton University
Washington Road
Princeton, NJ 08544-1014
Phone: 609-258-5657
E-mail: rdobrin at molbio.princeton.edu



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