[BioC] Fwd:gcRMA

James W. MacDonald jmacdon at med.umich.edu
Wed Jul 6 14:29:01 CEST 2005


claudio.is at libero.it wrote:
> hi to BioC list,
> 
> I have one question
> about gcRMA: if I
> run 
> 
> nor<-gcRMA(affy.data)
> 
> after the background
> correction, then
> what methods does it
> use? to me it's not
> clear if it use the
> usual quantile, pm
> only, tukey.biweight
> from justRMA or
> something else.

Yes, gcrma uses the normal rma model fit after background correction.

Best,

Jim


> 
> thanks in advance.
> 
> Isella Claudio
> 
> 
> 
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-- 
James W. MacDonald
Affymetrix and cDNA Microarray Core
University of Michigan Cancer Center
1500 E. Medical Center Drive
7410 CCGC
Ann Arbor MI 48109
734-647-5623



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