[BioC] LIMMA: uneven replication of samples

Jakob Hedegaard Jakob.Hedegaard at agrsci.dk
Fri Mar 4 08:58:01 CET 2005



I am going to analyze data from an cDNA microarray experiment conducted
to compare "diseased" and "healthy" pigs.

The experiment has been conducted as a "classical common reference"
experiment with the reference labeled with the same dye on all slides. A
total of 24 animals are included in the experiment (12 "diseased" and 12


Question: one of the "diseased" and one of the "healthy" animals have
been replicated three times resulting in a total of 28 slides.



How should this replication be handled in the analysis using LIMMA?



Looking forward hearing from you!




Jakob Hedegaard

Danish Institute of Agricultural Sciences

Department of Genetics and Biotechnology

Molecular Genetics and System Biology

Building K25

Research Centre Foulum

P.O. box 50

DK-8830 Tjele


Tel: (+45)89991363

Fax: (+45)89991300


	[[alternative HTML version deleted]]

More information about the Bioconductor mailing list