[BioC] background correction with cDNA array data

Giuseppe.Palermo@bo.infn.it Giuseppe.Palermo at bo.infn.it
Thu Oct 27 13:14:08 CEST 2005

I'm not sure if this can help you.
I also was interested in methods for background subtraction, and most 
of all in
understanding if or not subtract the background.
The only paper I found about last topic is:
"When should one subtract background fluorescence in two color 
microarrays", by
Parmigianini at. al.
Give a look, may be can help you.


Quoting Qi.Zhang at astrazeneca.com:

> Dear all,
> I have searched through the bioconductor ducument and this mailing list, but
> could not find a general guidance about how to correct background in cDNA
> array data.  I have imported my data (GPR files from GenePix) using
> functions from marray.  Now what are the available methods for background
> correction before normalization?  Any suggestions/experience is very much
> appreciated.
> Regards,
> Qi Zhang
> _______________________________________________
> Bioconductor mailing list
> Bioconductor at stat.math.ethz.ch
> https://stat.ethz.ch/mailman/listinfo/bioconductor

More information about the Bioconductor mailing list