[BioC] Combining replicate spots in CGH data

Sean Davis sdavis2 at mail.nih.gov
Wed Dec 6 19:42:37 CET 2006

On Wednesday 06 December 2006 11:12, João Fadista wrote:
> Dear all,
> I was wondering if there are other methods for combining replicate spots
> other than the average or the median. I am asking this in concern with CGH
> data analysis because I do not know how, and if, we can take advantage of
> the genomic structure of the array CGH data for combining replicate spots.
> For the sake of the argument I put below two hypothetical examples:
> - Combining replicate spots in a different way depending on what region of
> the chromosome or genome they are; - Or give more weight to spots that we
> know that have more reliability.

I don't think there are included in Bioconductor.  However, you can aggregate 
the data however you see fit, though it will mean writing some code to do so.


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