[BioC] Another question about dye swap

Gordon K Smyth smyth at wehi.EDU.AU
Thu Mar 2 22:24:32 CET 2006


It is a basic tenet of limma that the same model is fitted to each (all) of the genes.

Gordon

On Fri, March 3, 2006 5:24 am, Giorgi, Elena wrote:
> Hi,
>
> Is it possible to include the dye effect for those genes for which it's
> found to be significant and drop it for the others?
>
> I guess I could separate the two groups of genes and define a different
> design matrix for each group, but I'm wondering if there's also a way to
> produce a "dynamic" kind of design matrix...
>
> Thanks,
> Elena



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