[BioC] BioC normalisations for small array 2 colour data?

[Marcelo Luiz de Laia]

Dear Sean, Wolfgang Huber and All


Sean Davis wrote:
> I totally agree that simple single channel normalization is also problematic 
> in the situation where all genes are expected to be differentially expressed.  
>
>   

I have exactly this one: a one color array with 200 genes where all
genes are expected to be differentially expressed. I did vsn
normalization with default parameters. After this discussion, I am not
sure if I did the correct one? What is the suggestion in this situation?

Thank you very much


-- 
Marcelo Luiz de Laia
Ph.D Candidate
São Paulo State University (http://www.unesp.br/eng/)
School of Agricultural and Veterinary Sciences
Department of  Technology
Via de Acesso Prof.Paulo Donato Castellane s/n
14884-900   Jaboticabal - SP - Brazil
Fone: +55-016-3209-2675
Cell: +55-016-97098526