[BioC] Why "M" values?

James W. MacDonald jmacdon at med.umich.edu
Fri Sep 29 20:38:12 CEST 2006


Hi Jenny,

Jenny Drnevich wrote:
> Hi all,
> 
> Sorry to abuse the list with this general microarray question, but I was 
> hoping someone could quickly help me out with this... why are M-values 
> (log2(ratio of expression in A to B)) called M-values?

IIRC, it comes from MA plots, which are a plot of the log difference 
versus the log average (hence Minus vs Average ==> MvA plots).

Ya list abuser ;-D

Best,

Jim


> 
> Thanks,
> Jenny
> 
> Jenny Drnevich, Ph.D.
> 
> Functional Genomics Bioinformatics Specialist
> W.M. Keck Center for Comparative and Functional Genomics
> Roy J. Carver Biotechnology Center
> University of Illinois, Urbana-Champaign
> 
> 330 ERML
> 1201 W. Gregory Dr.
> Urbana, IL 61801
> USA
> 
> ph: 217-244-7355
> fax: 217-265-5066
> e-mail: drnevich at uiuc.edu
> 
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-- 
James W. MacDonald, M.S.
Biostatistician
Affymetrix and cDNA Microarray Core
University of Michigan Cancer Center
1500 E. Medical Center Drive
7410 CCGC
Ann Arbor MI 48109
734-647-5623


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