[BioC] Normalisation for 2-set microarray

Sean Davis sdavis2 at mail.nih.gov
Sun Apr 29 14:56:34 CEST 2007


Ольга Камнева wrote:
> Hello, all,
>
> I have a data from Affymetrix GeneChip Human Genome U133. Intensities from
> Array Set HG-U133A and  HG-U133B have a different distribution after
> normalisation (rma algorithm). What should I do? How can I combine these
> sets?
>   
Assuming you are going to be doing a gene-by-gene analysis, then you can 
probably use the combine() function from the Biobase package.  See the 
help for that command.

Sean



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