[BioC] filtering on variance

[Dennis.Burian at faa.gov]

I was planning to filter on summarized/normalized Affy expression data and
keep the genes in the high 50% of variance, but saw the recent paper on an
algorithm called FLUSH in NAR that filters on probe level data.  What is
the recommendation of the collective BioC consciousness about the stage in
data analysis that one should filter data using variance?

Dennis Burian, Ph.D.
Functional Genomics Group
Civil Aerospace Medical Institute, AAM-610
6500 S. MacArthur Blvd.
Oklahoma City OK  73169
405-954-6087
dennis.burian at faa.gov