[BioC] tilingArray question

Wolfgang Huber huber at ebi.ac.uk
Fri Nov 7 21:25:24 CET 2008

Anjan Purkayastha ha scritto:
>  From Huber et al, Bioinformatics 22 (16) 2006, 1963-1970, it appears 
> that parameters ci, di and delta need to be estimated from the data by 
> the user using the vsn package.  Is this assumption correct? Or does the 
> tilingArray package estimate these parameters from the data without any 
> user intervention?
> Tia,
> Anjan

Dear Anjan,

these parameters are estimated for you by the normalizeByReference 
function, you don't need to do anything else.

Try having a look at:
(user: readonly  password: readonly) and in particular the block in the 
end that is headed:
    ## call vsn, if there are >= 2 arrays

Hope this helps.
  Best wishes

Wolfgang Huber, EMBL-EBI, http://www.ebi.ac.uk/huber

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