[BioC] applying coxfilter after LIMMA

Adrian Johnson oriolebaltimore at gmail.com
Thu Nov 13 14:06:19 CET 2008

Dear group,

I have two types of samples (cancer and normal) with covariate data
including survival times.

I applied limma (and filtered genes that are significantly
differentially expressed between cancer and normal. Say I have 500
genes after (adj.P.Value using BH) filtering.

Is it meaningful to apply coxfilter on those 500 genes (by supplying
expression values for those 500 genes  and survival times for all
samples) instead of using kOverA flter.


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