[BioC] avereps function

Erika Melissari erika.melissari at bioclinica.unipi.it
Mon Apr 27 21:26:08 CEST 2009


Dear list,

does anyone use avereps function by limma package to average probe copies
on microarray?
I used this function and obtained a strange result: my differentially
expressed gene list sensibly change if I use or not this function (I
perform the average before lmFit and after normalization).
I know this function only averages probe copies that are on a microarray,
also if they are in multiple not fixed number.
What is the problem?

Thank you very much

Erika



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