[BioC] Question on LIMMA

Francisco Javier Burguillo burgui at usal.es
Tue Jul 7 10:41:01 CEST 2009

Dear colleages,

I can not uderstand a result I have. I made t-permutations and LIMMA to
find differentially expressed genes on the same 
dataset. Is it posible I can have
a gene which is overexpressed using t-permutations (t value = + something)
and underespressed using LIMMA (Statistic= - something) ?

Sorry but I can not fully understand the LIMMA algorithm yet.

Many thanks,


Fco. Javier Burguillo
Departamento de Química Física
Facultad de Farmacia
Universidad de Salamanca

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