[BioC] Illumina GoldenGate methylation array, methylumi

Jinyan Huang hiekeen at hotmail.com
Wed Aug 4 23:46:27 CEST 2010


Hi,

After normalized my data using methylumi, I used limma to find
different methylated genes. If I used the pvals as the weights, is it
reasonable?
I do like this.

w<-log(pvals(mldat),0.01)
fit1 <- lmFit(exprs(mldat.norm), dm,weights=w)

Thanks.



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