[BioC] meta-analysis with P values

Vincent Carey stvjc at channing.harvard.edu
Thu Jul 15 05:01:39 CEST 2010


This is really a question for R-help.  However, rmeta could be used if
you knew the study effect sizes and standard errors (see
meta.summaries).  Under certain assumptions you would be able to
derive a standard error for a given estimate from a p-value and sample
size.

On Wed, Jul 14, 2010 at 3:55 PM, Laura Rodriguez Murillo
<laura.lmurillo at gmail.com> wrote:
> Hi dear list,
>
> My question is on meta-analysis. I have three studies on the association of
> a SNP with a disease and I need to do a random-effects meta-analysis with my
> data. I only have the individual P value, the odds ratio and sample size
> from each study. I've checked rmeta and meta packages but it seems to me
> that I need to know the number of observations on each group, which I don't
> have in this case. Is there any other package I can use that accepts doing
> meta-analysis with these data?
>
> Thanks a lot for your help!
>
> Laura
>
>        [[alternative HTML version deleted]]
>
> _______________________________________________
> Bioconductor mailing list
> Bioconductor at stat.math.ethz.ch
> https://stat.ethz.ch/mailman/listinfo/bioconductor
> Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor
>



More information about the Bioconductor mailing list