[BioC] Combining raw images and locs files from different scans

[Aliaksei Holik]

Dear list members,

Hopefully, this will be a straightforward question. I had my samples 
analysed on Illumina beadchip by university services using iScan. When I 
received the data all images were in jpeg format and there were no locs 
files, I assume due to compressed image format. After some discussion 
with the services my chips were re-scanned producing tiff images and 
appropriate locs files. However, there was almost 3 weeks interval 
between the first and the second scans. I am concerned, therefore, that 
signal might have deteriorated and I'm thus wary of using the 
intensities data and images from the second scan.

My question is therefore, can I convert the original jpeg files in tiff 
format and combine them with locs files from the second scan to import 
the intensities data generated during the first scan using beadarray 
package. My reasoning being that no compression seemingly was applied to 
jpeg files and the same probes should be in different swaths during both 
first and the second scans. Please, correct me if I'm wrong.

Many thanks!

Aliaksei.