[BioC] limma question: lmFit with continuous predictor

[Gordon K Smyth]

Dear Bonnie,

The issue isn't so much between linear and logistic regression, as between 
differential expression (in the outcome is used to explain expression, as 
in limma) and prediction (in which expression is used to explain the 
outcome).

I don't work in the prediction and can't recommend packages.

Best wishes
Gordon

---------------------------------------------
Professor Gordon K Smyth,
Bioinformatics Division,
Walter and Eliza Hall Institute of Medical Research,
1G Royal Parade, Parkville, Vic 3052, Australia.
smyth at wehi.edu.au
http://www.wehi.edu.au
http://www.statsci.org/smyth

On Sat, 9 Jul 2011, Joubert, Bonnie (NIH/NIEHS) [E] wrote:

> I have a related question to limma .  I would like to run a logistic 
> model with my data where I have a dichotomous outcome and the predictor 
> variables are the methylation values (exprs(mldat)).  LmFit is for a 
> linear model only.  Is there a related package for performing logistic 
> regression?
>
> Thanks,
> Bonnie

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