[BioC] package/function for median center & unit variance

James F. Reid james.reid at ifom-ieo-campus.it
Mon Jul 11 15:24:24 CEST 2011


Hi Guido,

> After (RMA) normalization I would like to post-process my array data for downstream analyses by means of median centering and/or unit variance normalization.
> Does anyone know a library that contains these functions?
> Using available functions would minimize the chance on errors due my limited R coding skills... ;) I had a look at the library Genefilter but it doesn't contain these functions.

look at the functions scale and sweep.

HTH,
J.

>
> Thanks,
> Guido
>
> ---------------------------------------------------------
> Guido Hooiveld, PhD
> Nutrition, Metabolism&  Genomics Group
> Division of Human Nutrition
> Wageningen University
> Biotechnion, Bomenweg 2
> NL-6703 HD Wageningen
> the Netherlands
> tel: (+)31 317 485788
> fax: (+)31 317 483342
> email:      guido.hooiveld at wur.nl
> internet:   http://nutrigene.4t.com
> http://www.researcherid.com/rid/F-4912-2010
>
>
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