[BioC] Significance of variance

[Steve Lianoglou]

Hi,

It sounds like you are trying to look for differentially expressed
genes in your data.

Can you just go back and use the raw data that this "variance vector"
was calculated from and then use something more principled/sound like
limma?

-steve

On Mon, Jun 6, 2011 at 11:13 PM, Nitish Kumar Mishra
<nitishimtech at gmail.com> wrote:
> Hi All,
> I have single variance value for gene-expression of several genes (variance
> for several repeats of experiments), so in this way I have a single column
> (with 98,00 row) value of variance. Now I just want to check variance of
> which gene is statically significance.
>  eg;
>
> 1.2
> 0.9
> 1.6
> 1.5
> 0.07
> 1.03
> .
> .
> .
>
> In nutshell I was to calculate the different p-value for each single value.
> Can any one suggest how I can calculate the P-value for each value of column
> vector.
>
> Thanks in advanced.
> --
> Nitish Kumar Mishra
> 3104E, CBCB, Biomolecular Sciences Bldg #296
> University of Maryland, College Park, MD 20742
> Phone (Off): 301-405-8218
> Mobile No: 240-898-7311
> nitish at umiacs.umd.edu
> mishran at umd.edu
>
>        [[alternative HTML version deleted]]
>
> _______________________________________________
> Bioconductor mailing list
> Bioconductor at r-project.org
> https://stat.ethz.ch/mailman/listinfo/bioconductor
> Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor
>



-- 
Steve Lianoglou
Graduate Student: Computational Systems Biology
 | Memorial Sloan-Kettering Cancer Center
 | Weill Medical College of Cornell University
Contact Info: http://cbio.mskcc.org/~lianos/contact