[BioC] which statistical test to perform?

anand mt [guest] guest at bioconductor.org
Wed Nov 23 11:14:15 CET 2011


hi all,

i'm new to this microarray data  analysis.
recently i've been given data consisting of 11 tissues.
now i've normalized the data, filtered data using mas5 AP calls. My question is, which statistical test i must perform
to calculate the significance values ?? 

sample data is as below:


	accumbens	amygdala	cerebellum	corpus.collosum	hippocampus	midbrain	p.lobe	putamen	s.nigra	t.lobe	thalamus
1007_s_at	11.93852233	12.21404093	11.46118612	13.41594885	12.42216256	12.89589133	11.58715914	11.85803472	12.79920479	12.07087932	12.55338306
1053_at	7.490706858	7.526181155	7.551069308	7.891002293	7.49104271	7.971097552	8.088918072	7.660258014	7.92423132	7.54689645	7.128753703
117_at	8.486898268	8.773089087	7.642339349	8.560352732	7.676296801	7.865961146	7.250275943	7.929165261	7.874073766	7.940298941	8.10731601


I got some web results, from which i came to know that, chi-square test is of more relevant in this case (to compare 3 or more unmatched groups, binomial). Is it correct to choose chi-square test ??

Sorry if my question is too lame.

thanks in advance.

 -- output of sessionInfo(): 

R version 2.13.1 (2011-07-08)
Platform: i386-pc-mingw32/i386 (32-bit)

locale:
[1] LC_COLLATE=English_United States.1252  LC_CTYPE=English_United States.1252    LC_MONETARY=English_United States.1252 LC_NUMERIC=C                          
[5] LC_TIME=English_United States.1252    

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
[1] MASS_7.3-13

loaded via a namespace (and not attached):
[1] tools_2.13.1

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