[BioC] Probe level normalization

James W. MacDonald jmacdon at med.umich.edu
Wed Nov 30 16:00:42 CET 2011

Hi Suresh,

On 11/30/2011 7:49 AM, suri ghani wrote:
> How to perform the normalization using the individual probe expression values instead of the probeset expression values in Limma or any other bioconductor package??

I'm not sure what you are asking here. Could you please rephrase? What 
platform are you talking about here?

The term 'probeset' usually pertains to the Affymetrix microarray 
platform. If you are in fact using Affy data, then you won't use limma 
for normalization.

If you state clearly what you are trying to do, then maybe someone can help.



> Thanks in advance..
> Regards, 
> Suresh 
> 	[[alternative HTML version deleted]]
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James W. MacDonald, M.S.
Douglas Lab
University of Michigan
Department of Human Genetics
5912 Buhl
1241 E. Catherine St.
Ann Arbor MI 48109-5618

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