[BioC] differential gene set analysis

Gordon K Smyth smyth at wehi.EDU.AU
Wed Apr 18 12:23:05 CEST 2012


Dear Ed,

Quite a few tools, for example:

   library(limma)
   ?roast
   ?camera
   ?romer

Also for R-based gene sets:

   http://bioinf.wehi.edu.au/software/MSigDB/

Best wishes
Gordon

> Date: Tue, 17 Apr 2012 16:45:10 -0500
> From: Ed Siefker <ebs15242 at gmail.com>
> To: bioconductor <bioconductor at r-project.org>
> Subject: [BioC] differential gene set analysis
>
> Are there tools available for differential gene set analysis?
>
> e.g., if I apply the same treatment to two different cell lines,
> and find gene sets that are enriched in each with respect
> to untreated, can I compare the lists of gene sets and
> find ones that are significantly enriched in one but not
> the other?

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