[BioC] Optimisation

[Simon Noël]

   Hi every one,

   I have a big formula with some parameter that I want to minimise with some
   condition like sum  of all of them must be one, in some condition, one
   of them must equal 0, etc.

   I am trying to solve that with constrOptim but I got some broblem...  Like
   how  to have a parametter equal to 0  Is there any package who is more
   user friendly that you can suggest to me?

   Simon Noël
   CdeC