[BioC] Translating AB/BB/AA into a SNP with Illumina data

Lavinia Gordon lavinia.gordon at mcri.edu.au
Mon Jul 16 05:59:33 CEST 2012


Dear all,

I am working with Illumina Human Omni1 Quad data.  I only have access to
processed data, e.g:
ID_REF	VALUE	Score	Theta	R	B Allele Freq	Log R Ratio
200006	AB	0.8273118	0.4800678	2.651576
0.5337635	0.1516016

I would like to know what the SNP is at this position and wondered if
there are any components within the Bioconductor packages that can deal
with this data, taking into account the TOP/BTM strand approach that
Illumina uses.  I have previously had great success with crlmm, but that
was working from the raw IDAT files.

With thanks for your time,

Lavinia Gordon
Senior Research Officer
Quantitative Sciences Core, Bioinformatics

Murdoch Childrens Research Institute
The Royal Children's Hospital
Flemington Road Parkville Victoria 3052 Australia 
T 03 8341 6221
www.mcri.edu.au


______________________________________________________________________
This email has been scanned by the Symantec Email Security.cloud service.
For more information please visit http://www.symanteccloud.com



More information about the Bioconductor mailing list