[BioC] what difference to use edgeR in two different mode?

Dario Strbenac D.Strbenac at garvan.org.au
Thu Sep 13 02:00:41 CEST 2012

>dear ALL:
>i have 35 samples to find DE genes between "c0h" vs t0h", i can use
>such coding to reach the same
>aim, what is the difference? which one is  better?

The linear model is better than the exact test because you have a time course, which means the same biological organism measured repeatedly. You can't model organism-specific effects using the exact test.

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