[BioC] Apply non-Gaussian distribution data to limma

Jiang [guest] guest at bioconductor.org
Tue Dec 10 04:02:25 CET 2013

I have high through array data with two peaks in its distribution (raw and log 2 transformed). I googled it looks like is mixed Gaussian distribution - two normal distribution as some people suggested. I think limma's assumption is normal distribution. I was wondering if there is any way to fix the problem or to convert my data to normal distribution before applying to limma.


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see question

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