[BioC] ChIPpeakAnno "examplePattern.fa" file
Zhu, Lihua (Julie)
Julie.Zhu at umassmed.edu
Wed Feb 27 18:03:53 CET 2013
Jose,
Thanks for your kind word!
You might want to check out rGADEM package for de nova motif discovery.
Best regards,
Julie
On 2/27/13 11:29 AM, "José Luis Lavín" <joluito at gmail.com> wrote:
> Thank you Julie,
>
> I misunderstood the functionality and thought I was a "de novo" motif
> finder...
> Any insight on how to predict motifs from ChIPseq experiments? Any R module
> that does it and you can recommend? May you think of implementing this
> function to your awesome package?
> ;)
>
> JL
>
> 2013/2/27 Zhu, Lihua (Julie) <Julie.Zhu at umassmed.edu>
>> Jose,
>>
>> Thanks for the inquiry! I will add the following to the documentation.
>>
>> The examplePattern.fa, in fasta format, is included in the package as an
>> example pattern file for running function summarizePatternInPeaks. To use
>> this function, you will need to create your own custom pattern file with the
>> pattern(s) you are interested in searching in the peaks.
>>
>> The pattern file is in fasta file format. The base in the pattern consists
>> of IUPAC designated nucleotide symbols such as A, C, G, T, N, V, H, D....
>>
>> The bottom table on http://pgfe.umassmed.edu/ZFPsearch.html lists the
>> abbreviation codes for degenerate bases.
>>
>> Best regards,
>>
>> Julie
>>
>>
>> On 2/27/13 10:54 AM, "José Luis Lavín" <joluito at gmail.com> wrote:
>>
>>> When looking for motif occurrence in the peaks, the "examplePattern.fa" file
>>> you supply with the module:
>>>
>>> -Is a standard example pattern file you can use for any set under analysis
>>> or
>>> is it a custom one you include in the package referred to a particular set
>>> of
>>> motifs?
>>>
>>> -May you give a hint on how to create such kind of file myself?
>>>
>>> Thanks in advance
>>>
>>> JL
>>>
>>>
>>>
>>>
>>
>
>
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